Thomas E. McKone PhD

Adjunct Professor, Environmental Health Sciences
  • PhD - University of California, Los Angeles, 1981
  • PH 220C: Health Risk Assessment, Regulation, and Policy (Sp)
  • NUC ENG 275: Principles and Methods of Risk Analysis (F)
Research Interests: 
  • Risk assessment methods
  • Health tracking
  • Mass transfer at environmental and human/environment boundaries
  • Model uncertainty and reliability in exposure/risk assessment
  • Environmental and occupational radioactivity
Research Description: 

Dr. McKone's research interests include the use of multimedia compartment models in health-risk assessments; chemical transport and transformation in the environment; and measuring and modeling the biophysics of contaminant transport from the environment into the microenvironments with which humans have contact and across the human/environment exchange boundaries--skin, lungs, and gut. His most recent achievement in the area of exposure assessment involves the development of the CalTOX model for the California Department of Toxic Substances Control. This model addresses clean-up goals for contaminated soils and the contamination of adjacent air, surface water, sediments, and ground water. The modeling effort includes multimedia transport and transformation models, exposure scenario models, and efforts to quantify and reduce uncertainty in multimedia, multiple-pathway exposure models. The model is now being distributed by Cal-EPA and has attracted much attention both in the academic and regulatory communities. Dr. McKone is now working with the U.S. EPA to develop exposure models for regional air pollution and to develop exposure models for use with industrial ecology studies. Dr. McKone is also working with the U.S. EPA, the National Academy of Science, and the Environmental Defense Fund to evaluate health impacts of industrial releases to the air, water, and soil, and to assess the reliability of models used as indicators of health and environmental impact. 

Current Projects: 
  • Developing exposure models for regional air pollution and for use with industrial ecology studies
  • Evaluation of health impacts of industrial releases to the air, water, and soil, and to assessment the reliability of models used as indicators of health and environmental impact
Selected Publications: 

McKone TE, and Deshpande AW, "Can Fuzzy Logic Bring Complex Problems into Focus?" Environmental Science and Technology  39(1)A-pages feature, 2005

MacLeod MJ and McKone TE, "Overall Multi-Media Persistence as an Indicator of Potential for Population-Level Intake of Environmental Contaminants," Journal Environmental Toxicology and Chemistry, 23(10)2465-2472 2004

Lobscheid AB and McKone TE, "Constraining Uncertainties about the Sources and Magnitude of Polycyclic Aromatic Hydrocarbon (PAH) Levels in Ambient Air: the State of Minnesota as a Case Study," Atmospheric Environment, 38(33)5501-5515, 2004

McKone, TE and MacLeod MJ "Tracking Multiple Pathways of Human Exposure to Persistent Multimedia Pollutants: Regional, Continental, and Global Scale Models,” Annual Reviews of Environment and Resources, 28:463-492, 2004

Sohn MD, McKone TE, and Blancato JN, “Reconstructing population exposures from dose biomarkers: inhalation of trichloroethylene (TCE) as a case study” Journal of Exposure Analysis and Environmental Epidemiology , 14(3):204-213, 2004

McKone TE and Bennett DH, “Chemical-Specific Representation of Air-Soil Exchange and Soil Penetration in Regional Multimedia Models,” Environmental Science & Technology, 33(14):2123-2132, 2003

Other interests: 
  • Senior Staff Scientist and Deputy Department Health, Indoor Environment Department, Lawrence Berkeley National Laboratory
  • Member, Committee on Assessment of the Health Implications of Exposure to Dioxin, National Research Council, National Academy of Sciences, 2004 - present
  • Member, Committee on the Selection and Use of Models in the Regulatory Decision Process, National Research Council, National Academy of Sciences, 2003 - present
Profile Updated: January 31, 2005