John M. Colford Jr. MD, PhD, MPH

Chancellor's Chair
Professor of Epidemiology
Courses: 
  • PH 250B: Epidemiologic Methods
  • PH 252C: Intervention Trial Design
Research Interests: 
  • Waterborne infectious diseases (domestic, developing country, and recreational water settings)
  • Clinical trial design (individual and community-level)
Selected Publications: 

Colford, JM Jr., Hilton J, Wright C, Arnold B, Saha S, Wade T, Scott J, Eisenberg J. The Sonoma Water Evaluation Trial: A randomized drinking water intervention trial to reduce gastrointestinal illness in older adults.(Am J Public Health, 2009 Sep 17, epub ahead of print). PubMed PMID: 19762663

Mäusezahl D, Christen A, Pacheco GD, Tellez FA, Iriarte M, Zapata ME, Cevallos, M, Hattendorf J, Cattaneo MD, Arnold B, Smith TA, Colford JM Jr. Solar drinking water disinfection (SODIS) to reduce childhood diarrhoea in rural Bolivia: a cluster-randomized, controlled trial. PLoS Med. 2009 Aug;6(8):e1000125. Epub 2009 Aug 18. PubMed PMID: 19688036; PubMed Central PMCID: PMC2719054.

Arnold B, Arana B, Mäusezahl D, Hubbard A, Colford JM Jr. Evaluation of a pre-existing, 3-year household water treatment and handwashing intervention in rural Guatemala. Int J Epidemiol. 2009 Jul 2. [Epub ahead of print] PubMed PMID: 19574492.

Seto E, Soller J, Colford JM Jr, Strategies to Reduce Person-to-Person Transmission during widespread Escherichia coli O157:H7 Outbreak. Emerging Infectious Diseases 2007 Jun;13(6):860-6 PMID: 17553224

Arnold B and Colford JM Jr., Treating water with chlorine at point-of-use to improve water quality and reduced child diarrhea in developing countries: A systematic review and meta-analysis. Am J Trop Med Hyg. 2007 Feb;76(2):354-64. PMID: 17297049

Colford JM Jr, Wade TJ, Schiff KC, Wright CC, Griffith JF, Sandhu SK, Burns S, Hayes J, Sobsey M, Lovelace G, Weisberg S. Water quality indicators and the risk of illness at non-point source beaches in Mission Bay, California. Epidemiology 2007 Jan;18(1):27-35.

Eisenberg JNS, Hubbard A, Wade TJ, Sylvester MD, LeChevalier MW, Levy D, Colford JM Jr. Inferences drawn from a risk assessment compared directly with a randomized trial of a home drinking water intervention. Environmental Health Perspectives 2006 Aug;114:1199-1204

Colford JM Jr, Roy S, Beach MJ, Hightower A, Shaw SE, Wade TJ. A review of household drinking water intervention trials and an approach to the estimation of endemic waterborne gastroenteritis in the United States. Journal of Water and Health. 2006;4(Suppl 2):71-88.

Colford JM Jr, Saha SR, Wade TJ, Wright CC, Vu M, Charles S, Jensen P, Hubbard A, Levy DA, Eisenberg JN. A pilot randomized, controlled trial of an in-home drinking water intervention among HIV + persons. J Water Health. 2005 Jun;3(2):173-84. PMID: 16075942

Rees JR, Wade TJ, Levy DA, Colford JM Jr., Hilton JF. Changes in beliefs identify unblinding in randomized controlled trials: a method to meet CONSORT guidelines. Contemp Clin Trials. 2005 Feb;26(1):25-37. PMID: 15837450

Colford JM Jr., Wade TJ, Sandhu SK, Wright CC, Lee S, Shaw S, Fox K, Burns S, Benker A, Brookhart MA, van der Laan M, Levy D. A randomized controlled trial of in-home drinking water intervention for the reduction of gastrointestinal illness. Am J Epidemiol. 2005 Mar 1;161(5):472-82. PMID: 15718483

Fewtrell L, Kaufmann RB, Kay D, Enanoria W, Haller L, Colford JM Jr. Water, sanitation, and hygiene interventions to reduce diarrhoea in less developed countries: a systematic review and meta-analysis. Lancet Infect Dis. 2005 Jan;5(1):42-52. PMID: 15620560

Wade T, Sandhu S, Levy D, Lee S, LeChevalier M, Katz L, Colford J. Did a severe flood in the Midwest cause an increase in the incidence of gastrointestinal illness? American Journal of Epidemiology. 2004 Feb;159:398-405

Wade TJ, Pai N, Eiesenberg JNS, Colford JM Jr. Do US EPA water guidelines for recreational waters prevent gastrointestinal illness? A systematic review and meta-analysis. Environmental Health Perspectives. 2003 Jun;111:1102-9. PMID: 12826481

Eisenberg J.N.S., Lewis B. L., Porco T. C., Hubbard A. H., Colford JM Jr. Bias due to secondary transmission when estimating attributable risks reported from intervention trials. Epidemiology. 2003 Jul;14:442-50. PMID: 12843770

Khalakdina A, Vugia D, Nadle J, Rothrock G, Colford J. Is drinking water a risk factor for endemic cryptosporidiosis?: A case-control study in the immunocompetent general population of the San Francisco Bay Area? BMC Public Health 2003;3:11. PMID: 12689343

Eisenberg JNS, Wade TJ, Hubbard A, Abrams DI, Lesier RJ, Charles S, Vu M, Saha S, Wright CC, Levy DA, Jensen P, Colford JM Jr. Associations between water treatment methods and diarrhea in HIV positive individuals. Epidemiology and Infection 2002 Oct;129:315-23. PMID: 12405100

McCulloch M, Broffman M, Gao J, and Colford JM Jr. Chinese Herbal Medicine and Interferon in the Treatment of Chronic Hepatitis B: A Meta-Analysis of Randomized, Controlled Trials. American Journal of Public Health. 2002 Oct;92:1619-1628. PMID: 12356611

Colford JM Jr., Rees JR, Wade TJ, Khalakdina A, Hilton JF, Ergas IJ, Burns S, Benker A, Ma C, Bowen C, Mills D, Vugia D, Juranek D, and Levy D. Participant blinding and gastrointestinal illness in a randomized, controlled trial of an in-home drinking water intervention. Emerging Infectious Diseases 2002 Jan;8:29-36. PMID: 11749745

Wu YW and Colford JM Jr., Chorioamnionitis as a risk factor cerebral palsy: A meta-analysis. Journal of the American Medical Association, 2000 Sep 20;284(11):1417-24. PMID: 10989405.

Colford JM Jr., Tager I, Byers LF, Ricci P, Hubbard A, Horner R, Methods for assessing the public health impact of outflows from combined sewer systems. Journal of the Air and Waste Management Association, 1999 Apr, 49(4):454-62. PMID: 10232060.

Johnston SC, Colford JM Jr., and Gress DR. Oral contraceptives and the risk of subarachnoid hemorrhage: A meta-analysis. Neurology 1998 Aug;51(2):411-18. PMID: 9710012.

Colford JM Jr., Segal M, Tabnak F, Chen M, Sun R, Tager I. Temporal trends and factors associated with survival after Pneumocystis carinii pneumonia in California, 1983-1992. American Journal of Epidemiology, 1997 Jul 15; 146(2):115-127. PMID: 9230773.

Colford JM Jr., Tager IB, Hirozawa AM, Lemp GF, Aragon T, Petersen C. Cryptosporidiosis among patients infected with human immunodeficiency virus. Factors related to symptomatic infection and survival. American Journal of Epidemiology, 1996 Nov 1; 144(9):807-816. PMID: 8890659.

Profile Updated: September 28, 2016