Fenyong Liu PhD

Professor, Infectious Diseases
Research Interests: 
  • Biology of human viruses (e.g. herpes, cytomegalovirus)
  • Development of novel antiviral agents
  • Biochemistry of nucleic acids and RNA enzymes
Selected Publications: 

To, A., Bai, Y., Shen, A., Gong, H., Umamoto, S., and Liu, F. (2011). Yeast two hybrid analyses reveal novel binary interactions between human cytomegalovirus-encoded virion proteins. PLoS ONE. 6, e17796.

Bai, Y., Gong, H., Li, H.,Vu, G., Lu, S., and Liu, F. (2011). Oral delivery of RNase P ribozymes by Salmonella effectively inhibits viral infection in mice. Proc. Natl. Acad. Sci. USA. 108(8):3222-27.

Jiang, X., Bai, Y., Rider, P., Kim, K., Zhang, C., Lu, S., and Liu, F. (2011). Engineered external guide sequences effectively block viral gene expression and replication in cultured cells. J. Biol. Chem. 286(1):322-30.

Liu, F., and Altman, S. (2010) Ribonuclease P. Springer, New York.

Bai, Y., Li, H., Gong, H., Vu, G., Umamoto, S., Zhou, T., Lu, S., Liu, F. (2010) Salmonella-mediated delivery of RNase P ribozymes for inhibition of viral gene expression and replication in human cells. Proc. Natl. Acad. Sci. U.S.A. 107, 7269-7274.

Rider, P. J., Dunn, W., Yang, E., and Liu, F. (2009). Human cytomegalovirus microRNAs. Curr Top Microbiol Immunol, 325, 21-39.

Bai, Y., Trang, P., Li, H., Kim, K., Zhou, T., and Liu, F. (2008). Effective inhibition in animals of viral gene expression and pathogenesis by an engineered ribozyme derived from RNase P catalytic RNA. Proc. Natl. Acad. Sci. USA. 105, 10919-24.

Kim, K. and Liu, F. (2007). (Invited review) Inhibition of gene expression in human cells using RNase P-derived ribozymes and external guide sequences. Biochimica et Biophysica Acta. 1769, 603-612.

Hai, R., Chu, A., Li, H., Umamoto, S., Rider, P., Liu, F. (2006). Infection of human cytomegalovirus in cultured human gingival tissue. Virology J. 3:84.

Yu, X., Trang, P., Shah, S., Atanasov, I., Bai, Y., Zhou, Z. H. and Liu, F. (2005). Dissecting human cytomegalovirus gene function and capsid maturation by ribozyme targeting and electron cryomicroscopy. Proc. Natl. Acad. Sci. USA, 102, 7103-7108.

Lodoen, M., Abenes, G., Umamoto, U., Houchins, J. P., Liu, F., and Lanier, L. L. (2004). The Cytomegalovirus m155 Gene Product Subverts NK cell Antiviral Protection by Disruption of H60-NKG2D Interactions. J. Exp. Med. 200, 1075-1081.

Dunn, W., Chou, C., Li, H., Hai, R., Patterson, D., Stolc, V., Zhu, H., and Liu, F. (2003). Functional profiling of human cytomegalovirus genome. Proc. Natl. Acad. Sci. USA. 100, 14223-14228.


Profile Updated: August 11, 2011