Luoping Zhang, Ph.D.
Adjunct Professor, Division of Environmental Health Sciences
PHONE: (510) 643-5189
FAX: (510) 642-0427
LOCATION: 388 Li Ka-Shing Center
E-MAIL: luoping@berkeley.edu
WEBSITE: Division of Environmental Health Sciences
Courses
- PH 270C: Practical Toxicology
Research Interests
- Mechanisms of bone marrow toxicity caused by toxic chemicals, such as benzene, formaldehyde, etc.
- Application of systems biology (toxicogenomics, epigenomics, bioinformatics, phenomics) and RNAi in molecular epidemiological studies and in vitro experiments
- Environmental pollution and health effects in China
Selected Publications
Ren X, Ji Z, Yuh J, Tang M, Bersonda J, Smith MT and Zhang L (2013). The impact of FANCD2 deficiency on formaldehyde-induced toxicity in human lymphoblastoid cell lines. Arch Tox. 87(1):189-196. PMID: 22872141.
Zhang L, Bassig BA, Mora JL, Vermeulen R, Ge Y, Curry JD, Hu W, Shen M, Qiu C, Ji Z, Reiss B, McHale CM, Liu S, Guo W, Purdue MP, Yue F, Li L, Smith MT, Huang H, Tang X, Rothman N, Lan Q (2013). Alterations in serum immunoglobulin levels in workers occupationally exposed to trichloroethylene. Carcinogenesis. 34(4):799-802. PMID: 23276795.
Zhang L, Lan Q, Ji Z, Li G, Shen M, Vermeulen R, Guo W, Hubbard A, McHale CM, Rappaport SM, Hayes RB, Linet B, Yin S, Fraumeni JF, Rothman N, and Smith MT (2012). Leukemia-specific chromosomal loss detected in hematopoietic progenitor cells of benzene-exposed workers. Leukemia: 26(12):2494-8. PMID: 22643707.
McHale CM, Zhang L and Smith MT (2012). Current understanding of the mechanism of benzene-induced leukemia in humans: Implications for risk assessment. Carcinogenesis, 33(2):240-52. PMID: 22166497. PMCID: PMC3271273.
Zhang L, Lan Q, Guo W, Hubbard AE, Li G, Rappaport SM, McHale CM, Shen M, Ji Z, Vermeulen R, Yin S, Rothman N and Smith MT (2011). Chromosome-wide aneuploidy study (CWAS) in workers exposed to an established leukemogen, benzene. Carcinogenesis, 32(4):605-612. PMID: 21216845.
Ren X, McHale CM, Skibola CF, Smith AH, Smith MT and Zhang L (2011). An emerging role for epigenetic dysregulation in arsenic toxicity and carcinogenesis. Environ Health Perspect, 119(1):11-19. PMID: 20682481.
Ren X, Aleshin M, Jo WJ, Dills R, Kalman DA, Vulpe CD, Smith MT and Zhang L (2011). Involvement of N-6 Adenine-Specific DNA Methyltransferase 1 (N6AMT1) in Arsenic Biomethylation and Its Role in Arsenic-Induced Toxicity. Environ Health Perspect, 119(6):771-777. PMID: 21193388.
Duong A, Steinmaus C, McHale CM, Vaughan CP & Zhang L (2011). Reproductive and developmental toxicity of formaldehyde: a systematic review. Mutation Research Review. 728(3):118-38 PMID: 21787879.
Zhang L, McHale CM, Rothman N, Li G, Ji Z, Vermeulen R, Hubbard AE, Ren X, Shen M, Rappaport SM, North M, Skibola CF, Yin S, Vulpe C, Chanock SJ, Smith MT and Lan Q (2010). Systems biology of human benzene exposure. Chem Biol Interact, 184(1-2):86-93. PMID: 20026094.
Zhang L, Tang X, Rothman N, Vermeulen R, Ji Z, Shen M, Qiu C, Guo W, Liu S, Reiss B, Freeman LB, Ge Y, Hubbard AE, Hua M, Blair A, Galvan N, Ruan X, Alter BP, Xin KX, Li S, Moore LE, Kim S, Xie Y, Hayes RB, Azuma M, Hauptmann M, Xiong J, Stewart P, Li L, Rappaport SM, Huang H, Fraumeni JF, Jr., Smith MT and Lan Q (2010). Occupational exposure to formaldehyde, hematotoxicity, and leukemia-specific chromosome changes in cultured myeloid progenitor cells. Cancer Epidemiol Biomarkers Prev, 19(1):80-8. PMID: 20056626.
Tang X, Bai Y, Duong A, Smith MT, Li L and Zhang L (2009). Formaldehyde in China: production, consumption, exposure levels, and health effects. Environ Int, 35(8):1210-1224. PMID: 19589601.
Zhang L, Steinmaus C, Eastmond DA, Xin XK and Smith MT (2009). Formaldehyde exposure and leukemia: a new meta-analysis and potential mechanisms. Mutat Res Rev, 681(2-3):150-168. PMID: 18674636.
Profile updated: April 17, 2013