Daniel Portnoy, Ph.D.
Professor of Molecular and Cell Biology
PHONE: (510) 643-3925
FAX: (510) 643-5053
MAILING ADDRESS: 401 Barker Hall #3202
E-MAIL: portnoy@berkeley.edu
WEB SITE: http://mcb.berkeley.edu/labs/portnoy
Research Interests
- Intracellular Pathogens
- Listeria monocytogenes
- Cell Biology
- Innate immunity
Publications
O’Riordan, M., M. A. Moors, and D. A. Portnoy. Listeria intracellular growth and virulence require host-derived lipoic acid. Science. 302:462-464. (2003)
Lenz, L. L., S. Mohammadi, A. Geissler, and D. A. Portnoy. SecA2-dependent secretion of autolytic enzymes promotes Listeria monocytogenes pathogenesis. Proc. Natl. Acad. Sci. 100:12432-12437. (2003).
Cheng, L. W. and D. A. Portnoy. Drosophila S2 cells: an alternate infection model for Listeria monocytogenes. Cell Microbiol. 5:875-885 (2003)
Glomski, I., A. L. Decatur, and D. A. Portnoy. Listeria monocytogenes mutants that fail to compartmentalize LLO activity are cytotoxic, avirulent, and unable to evade host extracellular defenses. Infect. Immun. 71:6754-6765. (2003)
Bakardjiev, A. I., B. A. Stacy, S. J. Fisher, and D. A. Portnoy. Listeriosis in pregnant guinea pigs: A model of vertical transmission. Infect. Immun. 72:489-497. (2004)
McCaffrey, R., P. Fawcett, M. O’Riordan, K.D. Lee, E. A. Havell, P. O. Brown, and D. A. Portnoy. A specific gene expression program triggered by Gram-positive bacteria in the cytosol. Proc. Natl. Acad. Sci. 101:11386-91 (2004).
Auerbuch, V., D. G. Brockstedt, N. Meyer-Morse, M. O’Riordan, and D. A. Portnoy. Mice lacking the type I interferon receptor are resistant to Listeria monocytogenes. J. Exp. Med. 200:527-533. (2004).
Brockstedt, D. G, M. A. Giedlin, M. L. Leong, K. S. Bahjat, Y. Gao, W. Luckett, W. Liu, D. N. Cook, D. A. Portnoy, and T. W. Dubensky Jr. Cancer Immunotherapy using severly attenuated Listeria monocytogenes-based Vaccine Strains with enhanced immunogenicity and negligible toxicity. Proc. Natl. Acad. Sci. 101:13832-13837. (2004).
Profile Updated: December 14, 2007