Fenyong Liu, Ph.D.
Professor
PHONE: (510) 643-2436
FAX: (510) 643-9955
LOCATION: 326 Barker Hall
E-MAIL: liu_fy@berkeley.edu
Research Interests
- Biology of human viruses (e.g. herpes, cytomegalovirus)
- Development of novel antiviral agents
- Biochemistry of nucleic acids and RNA enzymes
Publications
To, A., Bai, Y., Shen, A., Gong, H., Umamoto, S., and Liu, F. (2011). Yeast two hybrid analyses reveal novel binary interactions between human cytomegalovirus-encoded virion proteins. PLoS ONE. 6, e17796.
Bai, Y., Gong, H., Li, H.,Vu, G., Lu, S., and Liu, F. (2011). Oral delivery of RNase P ribozymes by Salmonella effectively inhibits viral infection in mice. Proc. Natl. Acad. Sci. USA. 108(8):3222-27.
Jiang, X., Bai, Y., Rider, P., Kim, K., Zhang, C., Lu, S., and Liu, F. (2011). Engineered external guide sequences effectively block viral gene expression and replication in cultured cells. J. Biol. Chem. 286(1):322-30.
Liu, F., and Altman, S. (2010) Ribonuclease P. Springer, New York.
Bai, Y., Li, H., Gong, H., Vu, G., Umamoto, S., Zhou, T., Lu, S., Liu, F. (2010) Salmonella-mediated delivery of RNase P ribozymes for inhibition of viral gene expression and replication in human cells. Proc. Natl. Acad. Sci. U.S.A. 107, 7269-7274.
Rider, P. J., Dunn, W., Yang, E., and Liu, F. (2009). Human cytomegalovirus microRNAs. Curr Top Microbiol Immunol, 325, 21-39.
Bai, Y., Trang, P., Li, H., Kim, K., Zhou, T., and Liu, F. (2008). Effective inhibition in animals of viral gene expression and pathogenesis by an engineered ribozyme derived from RNase P catalytic RNA. Proc. Natl. Acad. Sci. USA. 105, 10919-24.
Kim, K. and Liu, F. (2007). (Invited review) Inhibition of gene expression in human cells using RNase P-derived ribozymes and external guide sequences. Biochimica et Biophysica Acta. 1769, 603-612.
Hai, R., Chu, A., Li, H., Umamoto, S., Rider, P., Liu, F. (2006). Infection of human cytomegalovirus in cultured human gingival tissue. Virology J. 3:84.
Yu, X., Trang, P., Shah, S., Atanasov, I., Bai, Y., Zhou, Z. H. and Liu, F. (2005). Dissecting human cytomegalovirus gene function and capsid maturation by ribozyme targeting and electron cryomicroscopy. Proc. Natl. Acad. Sci. USA, 102, 7103-7108.
Lodoen, M., Abenes, G., Umamoto, U., Houchins, J. P., Liu, F., and Lanier, L. L. (2004). The Cytomegalovirus m155 Gene Product Subverts NK cell Antiviral Protection by Disruption of H60-NKG2D Interactions. J. Exp. Med. 200, 1075-1081.
Dunn, W., Chou, C., Li, H., Hai, R., Patterson, D., Stolc, V., Zhu, H., and Liu, F. (2003). Functional profiling of human cytomegalovirus genome. Proc. Natl. Acad. Sci. USA. 100, 14223-14228.
Profile Updated: August 11, 2011