Darlene D. Francis, Ph.D.
Assistant Professor of Psychology and Public Health
PHONE: (510) 642-7132
FAX: (510) 642-5293
LOCATION: 3133 Tolman Hall
E-MAIL: darlenefrancis@berkeley.edu
Research Interests
- Developmental Psychobiology
- Stress
- Maternal Care
- Gene-Environment Interactions
- Environmental Regulation of Behavior
- Animal Models
Publications
Francis, D.D, Szegda, K., Campbell, G., Martin, W.D. and Insel, T.R. (2003). Epigenetic sources of behavioral differences in mice. Nature Neuroscience. 6 (5): 445-446.
Francis, D.D., Diorio, J., Plotsky, P.M. and Meaney, M.J. (2002). Environmental Enrichment reverses the effects of maternal separation on stress reactivity.
Francis, D.D. Young, L.J., Meaney, M.J. and Insel, T.R. (2002). Naturally occurring differences in material care are assiociated with the expression of oxytocin and vasopressin (V1a) receptors: gender differences. Journal of Neuroendocrinology. 14(14):349-353.
Francis,D.D. Champagne, F.C., and Meaney, M.J. (2000). Individual differences in maternal behavior are associated with variations in oxytocin receptor levels in rat. Journal of Neuroendocrinology. 12(12): 1145-1148.
Liu,D., Diorio, J., Day, J.C., Francis, D.D. and Meaney, M.J. (2000). Maternal care, hippocampal synaptogenesis and cognitive development in rats. Nature Neuroscience. 3(8): 799-806.
Meaney, M.J., Diorio, J., Francis, D.D., Weaver., S., Yau, J., Chapman, K. and Seckl, J.R. (2000). Poistnatal Handling increases the expression pf cAMP-inducible Transcription factors in the rat hippocampus: the Environmental enrichment reverses the Effects of maternal separation on stress reactivity effects of thyroid hormones and serotonin. Journal of Neuroscience. 20(10): 3926-3935.
Francis, D.D. Caldji, C., Champagne, F., Plotsky, P.M. and Meaney, M.J. (1999). The Role of corticotrophin-releasing factor <ETH> norepinepherine systems in mediating the effects of early experience on the development of behavioral and endocrine Responses to stress. Biological Psychiatry. 46(9):1153-1166.
Francis D.D., Diorio, J., Liu, D. and Meaney, M.J. (1999). Variations in maternal care Form the basis for a non-genomic mechanism of inter-generational transmission of individual differences in behavioral and endocrine responses to stress. Science. 286(5442):1155-8.
Francis, D.D. and Meaney, M.J. (1999). Maternal care and the development of syress responses. Curr Opin Neurobiol. 9, 128-134.
Lui, D., Diorio, J., Tannenbaum, B., Caldji, C., Francis D.D., Freedman. A., Sharma, S., Pearson, D., Plotsky, P.M., and Meaney, M.J. (1997) Maternal care, hippocampal glucocorticoid receptors, and hypothalamic-pituitary-adrenal responses to stress. Science. 277,1659-1662.
Profile updated: July 1, 2005