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Gertrude Case Buehring, Ph.D.
Professor of Virology and Associate Dean for Academic Affairs
PHONE: (510) 642-3870
FAX: (510) 642-6350
LOCATION: 61-A Koshland Hall
MAILING ADDRESS: 16 Barker Hall, MC 7354
E-MAIL: buehring@berkeley.edu

 

Courses

Research Interests

Current Projects

The following projects relate to our overall hypothesis that bovine leukemia virus (BLV) infects humans and could potentially cause cancer: 1) Does infection/transfection of normal human breast cells with BLV in culture cause them to acquire charactieristics of a malignant cell? 2) Is there a correlation among human serum antibodies to BLV, presence of BLV in leukocytes, and presence of BLV in breast tissues within individual humans? This is important in determining if blood serum or cells could be used diagnostically to identify women at risk of developing breast cancer. 3)Can women infected with BLV pass the virus to their children transplacentally or through breast milk? 4) Are other human organs besides breast infected by BLV and could it be associated with cancer in these organs?

Selected Publications

Joshi D, Buehring GC. Are Viruses associated with human breast cancer? Scrutinizing the molecular evidence. Breast Cancer Research and Treatment. Jan 25. Epub ahead of print.

Baltzell K, Buehring GC, et al. Epstein-Barr virus is seldom found in the mammary epithelium of breast cancer tissue using in situ molecular methods. Breast Cancer Research and Treatment (in press)

Lee LC, Scarret WK, Buehring GC, Saunders GK. Bovine leukemia virus infection in a juvenile alpaca with multicentric lymphoma. Canadian Veterinary Journal (in press)

Baltzell K, Buehring GC, Krishnamurthy S, Kuerer H, Shen HM, Sison JD. Limited evidence of human papillomavirus in breast tissue using molecular in situ methods. Cancer (in press)

Chantry CJ, Wiedemann J, Buehring GC, Peerson J, Hayfron K, Aluoch OK, Lonnerdal B, Israel-Ballard K, Coutsoudis A, Sibeko L, Abrams B. Effect of flash-heat treatment on antimicrobial activity of breastmilk. Breastfeeding Medicine. 2010 (Epub ahead of print)

Kittinunvorakoon C, Morris MK, Kanchana N, Bongkoch J, Buehring GC, Hanson C. Mother to Child Transmission of HIV in a Thai population: Role of virus characteristics and maternal humoral immune response. Journal of Medical Virology. 2009. 81:768-778.

Dumont N, Crawford YG,, Sigaroudinia M, Nagrani SS, Wilson MB, Buehring GC, Turashvili G, Aparicio S, Gauthier ML, Fordyce CA, McDermott KM, and Tlsty TD. Human mammary progression model recapitulates methylation events associated with breast premalignancy. 2009. Breast Cancer Research 11(6):R87(1-17).

Buehring, G.C., Shen, H-M, Jensen, H.M., Block, G. (2007). Bovine leukemia virus is significantly associated with risk of breast cancer. Proceedings of the American Association for Cancer Research 47:#1747.

Buehring, G.C., Letscher, A., McGirr, K., Khandar, S., Che, L., Nguyen, C., Hackett, A. (2006). Presence of epithelial cells in nipple aspirate fluid is associated with subsequent breast cancer: A 25-year prospective study. Breast Cancer Research and Treatment, 98, 63-70.

Buehring, G.C., Choi, K.Y., Philpott, S.M. (2003). Humans have antibodies reactive with bovine leukemia virus. AIDS Research and Human Retroviruses, 19, 1105-1113.

Motton, D.M., Buehring, G.C. (2003). Bovine leukemia virus alters growth properties and casein synthesis in mammary epithelial cells. Journal of Dairy Science, 86, 2826-38.

Philpott, S.M., Buehring, G.C. (1999). Defective DNA repair in cells infected with human T-cell leukemia/bovine leuekmia virus group. Journal of the National Cancer Institute, 91, 933-942.

Other Interests

Profile updated: February 1, 2012

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