Ernest B. Hook MD

Professor Emeritus
Research Interests: 
  • Epidemiology of birth defects & chromosome abnormalities
  • Capture-recapture methods in epidemiology
  • Human mutation, chromosome abnormalities, prenatal diagnosis
  • History and philosophy of medicine and science
Selected Publications: 

Hook EB (2006). Neural Tube Defects and Down Syndrome: How may we interpret the unexpected reported association in relatives? Down's Screening News 11 (1): 12-13, 2004.

Interpretation  of reported live birth maternal age-specific rates on an ostensibly white population in data from National 'Down Syndrome' Register. Prenatal Diagnosis 24(12): 1013-1024, 2004.  (Letter).

Temporal aspects of changes in neural tube defect rates. Birth Defects Research Part A - Clinical and Molecular Teratology 67(7): 531, Jul 2003.

Rates of Down syndrome at the upper extreme of maternal age: considerations and recommendations in analysis. Prenatal Diagnosis 26 (6): 586-587, Jun 2006.

Aspects of the early history of Down Syndrome. Down's Screening News 13(2): 10-11.

Hook EB, Regal RR (2004). Completeness of Reporting: Capture-Recapture Methods in Public Health Surveillance. In Monitoring the Health of Populations: Statistical Principles and Methods for Public Health Surveillance, R Brookmeyer, DF Stroup, eds., Oxford University Press, New York, pp. 341-359.

Hook EB, ed. (2002). Prematurity in Scientific Discovery: On Resistance and Neglect, pp. 408, University of California Press, California. A Background to Prematurity and Resistance to "Discovery". 3-21, in above: other chapters 124-48; 354-65.

Carothers AD, Castilla EE, Dutra M da G, Hook EB (2001). Search for ethnic, geographic, and other factors in the epidemiology of Down syndrome in South America: analysis of data from the ECLAMC project, 1967-1997. American Journal of Medical Genetics 103: 149-156.

Profile Updated: January 14, 2015