Postdoctoral training – Harvard University, Environmental Epigenetics (2018)
PhD – Oregon State University, Public Health (2015)
MPH – Oregon State University, Biostatistics (2012)
BSc – Oregon State University, Biochemistry & Biophysics (2010)
- Children's environmental health
- Environmental epidemiology
- Molecular epidemiology
Dr. Cardenas applies epidemiological and molecular approaches to evaluate the contribution of environmental exposures in the development of disease. He is currently investigating the prenatal influence of exposure to multiple metals, air pollution, endocrine disrupting compounds, diet and maternal medication use on the epigenome of newborns and children. His current research evaluates the role of environmental exposures in utero, epigenetic modifications, and their role in the developmental origins of health and disease.
“Mitochondrial DNA biomarkers of prenatal metal mixture exposure: intergenerational inheritance and infant growth” This is an ongoing collaboration with Harvard Medical School investigators of Project Viva; a prospective pre-birth cohort of mother-infant pairs, recruited in Eastern Massachusetts between 1999 and 2002. The objective for this project is to evaluate whether maternal prenatal exposure to metal mixtures in early pregnancy can disrupt molecular markers of mitochondrial DNA abundance and telomere length in mothers and children as a key mediators of metabolism and infant growth. The Children’s Health Exposure Analysis Resource (CHEAR) supports this study.
Cardenas A, Hauser R, Gold DR, Kleinman KP, Hivert MF, Fleisch AF, Lin PI, Calafat AM, Webster TF, Horton ES, Oken E. Association of Perfluoroalkyl and Polyfluoroalkyl Substances With Adiposity. JAMA Network Open. 2018. 1(4):e181493.
Cardenas A, Gagné-Ouellet V, Allard C, Brisson D, Perron P, Bouchard L, Hivert MF. Placenta DNA Methylation Adaptation to Maternal Glycemic Response in Pregnancy. Diabetes. 2018. 67(8):1673-1683
Bozack AK, Cardenas A, Quamruzzaman Q, Rahman M, Mostofa G, Christiani DC, Kile ML. DNA Methylation in Cord blood as Mediator of the Association between Prenatal Arsenic Exposure and Gestational Age. Epigenetics. 2018. 13(9):923-940.
Cardenas A, Rifas-Shiman SL, Agha G, Hivert MF, Litonjua AA, DeMeo DL, Lin X, Amarasiriwardena CJ, Oken E, Gillman MW, Baccarelli AA. Persistent DNA Methylation Changes Associated with Prenatal Mercury Exposure and Cognitive Performance During Childhood. Scientific Reports. 2017. 7(1):288.
Cardenas A, Rifas-Shiman SL, Godderis L, Duca RC, Navas-Acien A, Litonjua AA, DeMeo DL, Brennan KJ, Amarasiriwardena CJ, Hivert MF, Gillman MW, Oken E, Baccarelli AA. Prenatal Exposure to Mercury: Associations with Global DNA Methylation and Hydroxymethylation in Cord Blood and in Childhood. Environmental Health Perspectives. 2017. 125(8):087022.